Product Description
The BioDeviceLab 10 nm Silica Nanoparticles are precision-engineered, monodisperse amorphous SiO₂ nanospheres designed for advanced biological, analytical, and biodevice research. With a nominal diameter of ~10 nm, these nanoparticles provide a high surface-to-volume ratio that supports efficient biomolecule immobilization, surface chemistry modification, and controlled interaction with biological systems. Their chemically inert and optically transparent nature makes them ideal for biosensors, microfluidic devices, and lab-on-chip platforms where background interference must be minimized. Supplied as a stable aqueous dispersion, the 500 mL bulk format supports large-scale assay development and translational biodevice validation workflows.
Intended Use
This product is intended for research applications including:
• Biosensor surface modification and signal amplification
• Biomolecule immobilization and linker chemistry development
• Drug delivery and nanocarrier research
• Microfluidic and lab-on-chip material integration
• Cell interaction and uptake studies
• Reference nanomaterial for method development and validation
Principle of Operation
Silica nanoparticles act as inert, high-surface-area platforms for biological and chemical functionalization. The amorphous SiO₂ surface presents abundant silanol (–OH) groups that enable covalent attachment of proteins, antibodies, aptamers, and polymers. Their optical transparency avoids spectral interference in optical and electrochemical assays, while the small particle size supports dense functionalization and efficient surface interactions.
Characterization & Quality Control
Particle size and morphology are verified by transmission electron microscopy (TEM). Hydrodynamic diameter and dispersity are confirmed by dynamic light scattering (DLS), and zeta potential measurements assess colloidal stability. Standardized synthesis and QC protocols ensure batch-to-batch reproducibility.
Analytical & Physical Characteristics
Nominal particle diameter: ~10 nm
Material: Amorphous silica (SiO₂)
Morphology: Spherical
Size dispersity: <15%
Surface chemistry: Native silica (–OH rich)
Optical properties: Optically transparent (no SPR)
Dispersion medium: Aqueous
Supplied volume: 500 mL
Custom surface functionalization available upon request
Selectivity & Compatibility
Silica nanoparticles are chemically inert and broadly compatible with biological molecules, buffers, and microfluidic materials. Their non-plasmonic, non-conductive nature minimizes assay interference, supporting hybrid electrochemical, optical, and biochemical platforms.
Package Contents
Each unit contains:
• 500 mL of 10 nm silica nanoparticle aqueous dispersion
• Particle characterization and quality control documentation
Required Materials (Not Provided)
• DLS or TEM instrumentation (recommended)
• Standard laboratory glassware and pipettes
• Buffers suitable for downstream functionalization
Sample Handling & Use
Gently swirl before use to ensure uniform suspension. Avoid harsh agitation unless required for dispersion. Dilute using compatible buffers and handle with clean, contamination-free consumables.
Storage & Stability
Store at 4–25 °C. Do not freeze. Protect from prolonged contamination or evaporation. Stable under recommended storage conditions.
Limitations
For research use only. Not intended for diagnostic or therapeutic use. Performance may vary depending on surface modification strategy.
Applications
• Biosensor and biodevice surface engineering
• Microfluidic and lab-on-chip systems
• Nanomaterial–cell interaction studies
• Drug delivery and nanocarrier development
• Biodevice calibration and benchmarking
