Product description
The BioDeviceLab Blood–Brain Barrier (BBB)-on-Chip Microfluidic Platform recreates the structural and functional properties of the neurovascular interface using two parallel microchannels separated by a thin porous membrane. The upper channel supports brain endothelial cells under physiologically relevant shear stress, while the lower channel enables perfusion with supporting cell types or test compounds to evaluate transport and barrier integrity. The clean, straight channel geometry minimizes dead volume and ensures reproducible flow profiles, supporting long-term culture and quantitative permeability studies. Fabricated from optically transparent, biocompatible polymer, the chip enables high-resolution imaging and seamless integration with modular microfluidic workflows.
Key features
Dual-channel architecture for endothelial barrier modeling
Integrated porous membrane for selective transport studies
Uniform channel geometry for predictable shear stress
Optically transparent for live-cell imaging and TEER-compatible layouts
Low dead-volume microfluidic design
Reservoir- or Luer-compatible interfacing
Applications
Blood–brain barrier permeability and transport studies
CNS drug screening and delivery assessment
Neuroinflammation and immune transmigration assays
Disease modeling of BBB dysfunction
Integration into multi-organ brain–periphery models
