Product description
The BioDeviceLab Gut-on-Chip Microfluidic Platform is designed to replicate key structural and functional aspects of the human intestine by integrating villus-like microarchitectures within a perfused microfluidic channel. The elongated channel geometry supports physiologically relevant shear stress, while the villus-inspired structures increase surface area and promote realistic epithelial differentiation, polarization, and barrier formation. The platform can be configured as a single-channel epithelial model or as a dual-channel system with an underlying perfusion channel for immune, endothelial, or microbial interaction studies. Fabricated from optically transparent, biocompatible polymer, the chip enables high-resolution imaging, long-term culture, and seamless integration with upstream and downstream microfluidic modules.
Key features
Villus-inspired microstructures to enhance surface area and physiology
Perfused microchannel supporting intestinal shear stress conditions
Supports long-term epithelial culture and barrier formation
Optically transparent for real-time imaging and analysis
Low dead-volume microfluidic design
Compatible with reservoir-based or Luer-lock interfacing
Applications
Gut and intestinal barrier modeling
Microbiome–host interaction studies
Drug absorption and permeability testing
Inflammation and epithelial injury models
Nutrition, metabolite, and toxicity studies
